Non-steroidal anti-inflammatory drugs and adverse renal effects.

Non-steroidal anti-inflammatory drugs.

Renal impairment in relation to non-steroidal anti-inflammatory drugs.

Correspondence Renal impairment in relation to non-steroidal anti-inflammatory drugs SIR, Unsworth et al have recently shown that asymptomatic, reversible impairment of renal function is common in patients with rheumatoid arthritis (RA) receiving long term non-steroidal anti-inflammatory drug (NSAID) treatment .' This conclusion was derived from the observation that when NSAID treatment in 11 p...

Renal impairment associated with non-steroidal anti-inflammatory drugs

SIR, The study by Unsworth et al' would appear to have methodological deficiencies which limit both its conclusions and its applicability to rheumatic patients taking nonsteroidal anti-inflammatory drugs (NSAIDs). These include the reason for choosing to discontinue the medication in a particular individual; the lack of information about the reason for admission of the patients, and particularl...

Renal impairment associated with non-steroidal anti-inflammatory drugs

SIR, The study by Unsworth et al' would appear to have methodological deficiencies which limit both its conclusions and its applicability to rheumatic patients taking nonsteroidal anti-inflammatory drugs (NSAIDs). These include the reason for choosing to discontinue the medication in a particular individual; the lack of information about the reason for admission of the patients, and particularl...

Renal impairment associated with non-steroidal anti-inflammatory drugs.

We have compared the renal function on admission and discharge of 22 patients routinely admitted to our rheumatology ward. None had previously diagnosed renal failure. Of 11 patients in whom we stopped long term non-steroidal anti-inflammatory drug (NSAID) therapy, all showed a rise in creatinine clearance (Ccr) after three to 28 days. In contrast, a control group comprising 11 similar patients...